What Is Intraductal Papilloma of the Breast?
Intraductal papilloma refers to a benign papillary tumor arising from the epithelium of the breast ducts. It can occur in any female after puberty, particularly common in multiparous women, especially those aged 40–50. The malignancy rate reaches 5–10%, classifying it as a precancerous lesion, warranting clinical attention. Biopsy or fine-needle aspiration cytology may be necessary when needed. It is generally believed that this condition is associated with excessive estrogen stimulation. Nipple discharge: intermittent, spontaneous bleeding or serosanguinous fluid. About 20% of cases present a palpable nodule or cord-like mass in the areolar region, typically small (usually 0.5–1 cm), occasionally exceeding 2 cm. Most cases are painless, though larger tumors blocking ducts may cause pain, which eases after discharge. Generally, single large intraductal papillomas are more likely to cause discharge, whereas multiple smaller ones have a lower chance.
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